roadRunner is a high performance cellular network simulation. roadRunner accepts standard SBML Level 2 and generates the necessary ordinary differential equations that are solved either by CVODE to generate time course data or NLEQ to compute the steady state.
roadRunner supports many functions, including:
ODE simulation and steady state analysis
Conservation analysis to ensure a non-singular Jacobian
Steady state metabolic control analysis
Frequency domain metabolic control analysis
Simple continuation of steady states
roadRunner is of primary interest to developers by way of providing a standard simulation resource for SBW. Non-developers can access roadRunner from either JDesigner and SimDriver or for more technically minded users, scripting languages such as Python or Matlab.
roadRunner has no graphical user interface but runs as a background service, accepted SBML models and generating solutions. The screen shot shown here is taken from an inspector screen shot illustrating some of the SBW method functions available in roadRunner. roadRunner supports three levels from the SBW simulator API.
roadRunner is installed with SBW. For more information see the SBW installation page.
roadRunner is written in C# and has been ported to Linux and Mac OS using Mono. roadRunner is fully supported on Windows, Mac OS X, and Linux.